Ukoliko je doneta odluka o propisivanju diazepama istovremeno sa opioidima, treba primenjivati najmanju efektivnu dozu a trajanje terapije treba ograničiti na što kraće vreme (videti i opšte preporuke doziranja u odeljku four.2).
Predloženi mehanizam interakcije je kompetitivno vezivanje teofilina za adenozinske receptore u mozgu. Na taj način onemogućava se farmakodinamsko dejstvo diazepama, dolazi do npr. smanjenja sedativnog i psihomotornog dejstva diazepama.
Similar to other opioids, tramadol selectively binds to various opiate receptors in the central anxious technique on account of its opioid nature. Fast-launch tramadol is not supposed for use as an "as wanted" medication but relatively for ache episodes Long lasting a lot less than every week. In distinction, extended-release tramadol is the preferred choice for ache persisting past per week, and its indication lies in delivering 24-hour ache management or prolonged relief.
The existence of other health-related complications could have an effect on the usage of this medicine. Ensure you inform your physician When you have every other medical complications, Primarily:
Ukoliko mislite da se nešto od navedenog odnosi na Vas ili ako imate bilo kakve nedoumice, posavetujte se sa Vašim lekarom pre nego što uzmete lek Bensedin.
Psychological dependence (habit) is unlikely to happen when narcotics are used for this function. Physical dependence could cause Unwanted effects once you quickly prevent taking the medicine. Due to the fact this drugs is simply employed for brief-expression relief of suffering, psychological and Bodily dependence will most likely not manifest.
For the duration of pregnancy, this medication need to be used only when Evidently needed. It might harm an unborn baby. Examine the threats and Added benefits with all your health care provider.
Istovremena primena leka Bensedin i opioida (lekova za ublažavanje jakih bolova, lekova za supstitucionu terapiji i određenih lekova protiv kašlja) povećava rizik od pospanosti, otežanog disanja (respiratorna depresija), kome što sve može biti životno ugrožavajuće. Zbog toga istovremenu primenu treba razmotriti samo ukoliko druge terapijske opcije nisu moguće.
Making use of this medicine while you're pregnant might result in really serious undesirable results, such as neonatal withdrawal syndrome in the new child child. Inform your medical doctor right away if you believe that you are Expecting or if you intend to be Expecting when employing this medication.
Some side effects may arise that typically usually do not check here will need clinical consideration. These side effects could go away during remedy as your body adjusts towards the medicine. Also, your well being treatment Qualified might be able to let you know about approaches to forestall or lower A few of these Negative effects.
If somebody has overdosed and has significant signs and symptoms such as passing out or issues breathing, give them naloxone if accessible, then connect with 911. If the person is awake and it has no signs, connect with a poison control Heart right away.
Istovremena primena sa ovim lekovima može pojačati sedativni efekat i uzrokovati depresiju respiratorne i kardiovaskularne funkcije. Istovremena primena sa narkotičkim analgeticima može pospešiti psihičku zavisnost zbog pojačavanja euforičnog efekta.
This drugs may be behavior-forming. In case you feel that the medication isn't Doing the job at the same time, don't use in excess of your prescribed dose. Get in touch with your health care provider for instructions.
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